Effects of oncogenic mutations on the conformational free-energy landscape of EGFR kinase
PNAS June 10, 2013
http://www.pnas.org/content/early/2013/06/07/1221953110.short
http://www.pnas.org/content/early/2013/06/07/1221953110.short
I can't say I'm a fan of purely computational work without a healthy dose of experimental evidence, but this is nonetheless a nice paper on the dynamics of EGFR.
