Target Binding Properties and Cellular Activity of Afatinib (BIBW 2992), an Irreversible ErbB Family Blocker
J Pharmacol Exp Ther. 2012 Nov;343(2):342-50
Normally I would discuss this paper, but it appears that there is a whole other paper devoted to it and the crystal structure it reports:
EGFR: Tale of the C-terminal tail
Protein Sci. 2013 May 15
http://onlinelibrary.wiley.com/doi/10.1002/pro.2283/abstract
